Celther has developed Celther human induced neurons derived from iPS cells.

This readily and stably available human neurons will have enormous contribution to understanding the mechanism of human nervous system as well as provide a unique in vitro system for preclinical drug discovery, neurotoxicity testing, predictive disease modeling, and basic cellular research .

Celther neural cell products and services can be flexibly tailored for the customers' needs by genetic manipulation, making patient-derived neurons or any other collaborations.

These cells quickly assume a typical neuronal morphology with branching neurites. Antibodies to MAP2 are markers on neuronal cells, their perikarya and neuronal dendrites. In contrast tau is found predominantly in neuronal axons. Celther Neurons are both MAP2 and TAU positive in immunocytochemical staining.

In addition, Celther neurons display a stable adherent single-cell morphology and remain viable for an extended culture period (>=14 days), making them amenable to a variety of electrophysiology, neurotoxicity, and synaptic neurotransmission assays. Easy to implement and available in commercial quantities, these high quality, highly pure neurons are are cryopreserved at passage one. Once thawed, Celther neurons remain viable for extended culture periods, allowing for acute and chronic studies.